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Title: Brazilian berry extract ( Myrciaria jaboticaba ): A promising therapy to minimize prostatic inflammation and oxidative stress Author: Lamas, Celina A.; Kido, Larissa A.; Hermes, Túlio A.; Nogueira'lima, Ellen; Minatel, Elaine; Collares'buzato, Carla B.; Maróstica, Mário R.; Cagnon, Valéria h. A. Year: 2020 Is part of: The Prostate, v. 1, p. 1 - 13 DOI: https://doi.org/10.1002/pros.24017 Citation: Lamas, Celina A.; Kido, Larissa A.; Hermes, Túlio A.; Nogueira'lima, Ellen; Minatel, Elaine; Collares'buzato, Carla B.; Maróstica, Mário R.; Cagnon, Valéria h. A.; Brazilian berry extract ( Myrciaria jaboticaba ): A promising therapy to minimize prostatic inflammation and oxidative stress. The Prostate, v.1, p. 1-13, 2020 Abstract: Background Brazilian berry is a fruit popularly known as "Jaboticaba," rich in bioactive compounds with antioxidant and anti-inflammatory properties. Senescence and overweight are increasing worldwide and are considered risk factors to prostatic pathogenesis mainly due to oxidative and inflammatory processes induction. Thus, this study aimed to evaluate the effect of two increasing doses of the patented jaboticaba peel extract (PJE) on oxidative-stress and inflammation in the prostate of aging or high-fat-fed aging mice. Funding: This study was financed by the Coordination of Superior Level Staff Improvement-Brazil (Finance Code 001), by the National Council for Scientific and Technological Development (CNPq-141766/2015-8) and the SAo Paulo Research Foundation (FAPESP-2015/25714-1). Mario R. Marostica Junior acknowledges CNPq (403328/2016-0; 301108/2016-1), FAPESP (2015/50333-1; 2018/11069-5), and Iberoamerican Red of Underutilized Autochthonous Foods (ALSUB-CYTED, 118RT0543). |
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