Article

Download article 		Title: Nanohybrid hydrogels designed for transbuccal anesthesia
Author: Ribeiro, L. N. M.; Franz-montan, M.; Breitkreitz, M. C.; Rodrigues Da Silva, Gustavo H.; Castro, S. R.; Guilherme, V. A.; Araujo, D.R.; De Paula, Eneida
Year: 2018
Is part of: International Journal of Nanomedicine, v. Volume 13, p. 6453 - 6463
DOI: https://doi.org/10.2147/ijn.s180080

Citation: Ribeiro, L. N. M.; Franz-montan, M.; Breitkreitz, M. C.; Rodrigues Da Silva, Gustavo H.; Castro, S. R.; Guilherme, V. A.; Araujo, D.R.; De Paula, Eneida; Nanohybrid hydrogels designed for transbuccal anesthesia. International Journal of Nanomedicine, v.Volume 13, p. 6453-6463, 2018

Abstract: Background: Local anesthesia in dentistry is by far the most terrifying procedure for patients, causing treatment interruption. None of the commercially available topical formulations is effective in eliminating the pain and phobia associated to the needle insertion and injection.

Keywords: buccal anesthesia; drug-delivery; hybrid hydrogel; lidocaine; local anesthetics;
Subjects: CIENCIAS_BIOLOGICAS; Farmacologia Bioquímica e Molecular; CIENCIAS_BIOLOGICAS; Biofísica; Biofísica de Processos e Sistemas;

Funding: The authors thank FAPESP (#1425372-0, #14/14457-5) and Cristalia Ind. Quim. Farm. Ltda, for kindly providing lidocaine and prilocaine. 		Financed by: