Article

Download article 		Title: Recent advances and perspectives in topical oral anesthesia
Author: Franz-montan, Michelle; De Paula, Eneida; Ribeiro, Lígia Nunes De Morais; Volpato, Maria Cristina; Cereda, Cintia Maria Saia; Groppo, Francisco Carlos; Tofoli, Giovana Randomille; De Araújo, Daniele Ribeiro; Santi, Patrizia; Padula, Cristina
Year: 2017
Is part of: Expert Opinion on Drug Delivery, v. 14, p. 673 - 684
DOI: https://doi.org/10.1080/17425247.2016.1227784

Citation: Franz-montan, Michelle; De Paula, Eneida; Ribeiro, Lígia Nunes De Morais; Volpato, Maria Cristina; Cereda, Cintia Maria Saia; Groppo, Francisco Carlos; Tofoli, Giovana Randomille; De Araújo, Daniele Ribeiro; Santi, Patrizia; Padula, Cristina; Recent advances and perspectives in topical oral anesthesia. Expert Opinion on Drug Delivery, v.14, p. 673-684, 2017

Abstract: Introduction: Topical anesthesia is widely used in dentistry to reduce pain caused by needle insertion and injection of the anesthetic. However, successful anesthesia is not always achieved using the formulations that are currently commercially available. As a result, local anesthesia is still one of the procedures that is most feared by dental patients. Drug delivery systems (DDSs) provide ways of improving the efficacy of topical agents.

Keywords: cyclodextrins; dentistry; drug delivery; liposomes; oral mucosa; polymers;
Subjects: CIENCIAS_BIOLOGICAS; Farmacologia Bioquímica e Molecular;

Funding: Financial support for this work was provided by the Sao Paulo Research Foundation (FAPESP, grants 2012/06974-4 and 2014/14457-5). 		Financed by: