Cargo: Professor Doutor I
PhD, The University of Sheffield
Dep. BIOQUÍMICA E BIOLOGIA TECIDUAL, IB, Unicamp, Campinas, SP
leotrosa@unicamp.br
Researcher fascinated by microbial physiology, characterizing bacterial transport and pathogenicity mechanisms by structural, biochemical and microbiological approaches, with focus on the Tripartite Tricarboxylate Transport family (TTT). Currently works as associated professor at Biochemistry institute in Campinas State University (UNICAMP). Worked as postdoctoral researcher in the Chemistry institute ? University of São Paulo, characterizing bacterial secretion systems by CryoEM, and for 3,5 years as Postdoctoral researcher in the Institut Européen de Chimie et Biologie (Pessac-FR), specializing in the SPA-CryoEM analysis of the transformassome apparatus in gram positive bacteria. Obtained a PhD from The University of Sheffield (UK), working on the TTT family in the photosynthetic bacteria Rhodopseudomonas palustris. Graduated in Biotechnology in 2013, in the Federal university of Sao Carlos, with a sandwich period in The University of Sheffield(UK) as part of the program Science Without Borders. Ongoing member of the Higher Education Academy since 2016.
Pesquisador fascinado por fisiologia microbiana, caracterizando o mecanismo de transporte membranar e patogenicidade bacteriana por abordagens estruturais, bioquímicas e microbiológicas. Especialista em biologia estrutural por Análise de Partícula Única - CryoEM. Atualmente foca no estudo da família Tripartite Tricarboxylate Transport (TTT) no patógeno Bordetella pertussis. Gostou do tema? Venha trabalhar com a gente! Vagas abertas para mestrado e Doutorado Direto
rosa, Leonardo T; Dix, Samuel R; Rafferty, John B; Kelly, David J; Structural basis for high-affinity adipate binding to AdpC (RPA4515), an orphan periplasmic binding protein from the Tripartite Tricarboxylate Transporter (TTT) family in. FEBS Journal, v.-, p. 14304-, 2017 [ doi:10.1111/febs.14304 ]
rosa, Leonardo T.; Dix, Samuel R.; Rafferty, John B.; Kelly, David J.; A New Mechanism for High-Affinity Uptake of C4-Dicarboxylates in Bacteria Revealed by the Structure of Rhodopseudomonas palustris MatC (RPA3494), a Periplasmic Binding-Protein of the Tripartite Tricarboxylate Transporter (TTT) Family. JOURNAL OF MOLECULAR BIOLOGY, v.1, p. YJMBI 65926-, 2018 [ doi:10.1016/j.jmb.2018.11.016 ]
Jur'nas, Dukas; rosa, Leonardo Talachia; Rey, Martial; Chamot-rooke, Julia; Fronzes, Rémi; Cascales, Eric; Mounting, structure and autocleavage of a type VI secretion-associated Rhs polymorphic toxin. Nature Communications, v.12, p. 6998-, 2021 [ doi:10.1038/s41467-021-27388-0 ]
rosa, Leonardo Talachia; Vernhes, émeline; Soulet, Anne-lise; Polard, Patrice; Fronzes, Rémi; Structural insights into the mechanism of DNA branch migration during homologous recombination in bacteria. The EMBO Journal, v.1, p. online-, 2024 [ doi:10.1038/s44318-024-00264-5 ]
rosa, Leonardo T.; Bianconi, Matheus E.; Thomas, Gavin H.; Kelly, David J.; Tripartite ATP-Independent Periplasmic (TRAP) Transporters and Tripartite Tricarboxylate Transporters (TTT): From Uptake to Pathogenicity. Frontiers in Cellular and Infection Microbiology, v.8, p. 324356-, 2018 [ doi:10.3389/fcimb.2018.00033 ]
Lattes CV
0000-0003-0527-6391
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