Eneida de Paula

Personal photo

Cargo: Professor Colaborador

professor titular / Unicamp

Dep. BIOQUÍMICA E BIOLOGIA TECIDUAL, IB, Unicamp, Campinas, SP

depaula@unicamp.br

Area

  • Biotechnology

Research lines

  • Macromolecules Chemistry

Academic Background

Nurse bachelor at Universidade Estadual de Campinas, Unicamp (1985), master in Biochemistry at Unicamp (1988) and Ph.D in Biochemistry at Universidade de São Paulo (1993); Full professor in Biochemistry, Unicamp (2010). Has experience in Byophysics, Biochemistry and pharmacy, focusing on Drug delivery and Biomimetic systems, focusing the interaction of active molecules (local anesthetics, anticancer drugs) with carriers such as liposomes, nanostructured lipid carriers, cyclodextrins).

Research activities

Biochemical pharmacology and pharmaceutical technology: 1) Development and characterization of drug-delivery systems in carriers such as cyclodextrins, liposomes, Nanostructured lipid carriers; 2) Biochemistry and Biophysics applied to the study of amphiphile interaction with biomimetic systems.

Teaching activities

biochemistry Biological and model membranes

Selected Publications

De Paula, E.; Schreier, Shirley; Use of a novel method for determination of partition coefficients to compare the effect of local anesthetics on membrane structure. Biochimica et Biophysica Acta. Biomembranes, v.1240, p. 25-33, 1995 [ doi:10.1016/0005-2736(95)00155-6 ]

Pinto, Luciana De Matos Alves; Yokaychiya, Daniela Kiyoko; Fraceto, Leonardo Fernandes; De Paula, E.; Interaction of benzocaine with model membranes. Biophysical Chemistry (Print), v.87, p. 213-223, 2000 [ doi:10.1016/s0301-4622(00)00196-4 ]

Fraceto, Leonardo Fernandes; Oyama, Sérgio; Nakaie, Clóvis R; Spisni, Alberto; De Paula, E.; Pertinhez, Thelma De Aguiar; Interaction of local anesthetics with a peptide encompassing the IV/S4-S5 linker of the Na+ channel. Biophysical Chemistry (Print), v.123, p. 29-39, 2006 [ doi:10.1016/j.bpc.2006.03.010 ]

Preté, Paulo S.C.; Domingues, Cleyton C.; Meirelles, Nilce C.; Malheiros, Sônia V.P.; Goñi, Félix M.; De Paula, Eneida; Schreier, Shirley; Multiple stages of detergent-erythrocyte membrane interaction¿A spin label study. Biochimica et Biophysica Acta. Biomembranes, v.1808, p. 164-170, 2011 [ doi:10.1016/j.bbamem.2010.10.016 ]

De Araújo, Daniele Ribeiro; Ribeiro, Lígia Nunes De Moraes; De Paula, Eneida; Lipid-based carriers for the delivery of local anesthetics. Expert Opinion on Drug Delivery, v.16, p. 701-714, 2019 [ doi:10.1080/17425247.2019.1629415 ]