Personal presentation

graduate at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1990), master's at Anatomy from Universidade Estadual Paulista Júlio de Mesquita Filho (1993) and ph.d. at Anatomy from Universidade Estadual Paulista Júlio de Mesquita Filho (1996). Has experience in Morphology, focusing on Human Anatomy, acting on the following subjects: biologia celular e estrutural, prostate, morfologia, ultra-estrutura and próstata.

Research activities

The Laboratory of Reproductive Biology has studied the prostatic microenvironmental changes such as proliferative lesions associated or not with the aging process. The prostatic stroma dynamics as well as the stroma-epithelium interaction have also been the focus of our research, due to the main roles of these glandular compartments in the development and progression of the prostatic lesions associated with inflammation; angiogenesis; and oxidative stress. These studies have used different therapies, including those with natural compounds such as Brazilian berries, and a transgenic adenocarcinoma of the mouse prostate (Tramp) model. In addition to this, biological techniques for instance, immunohistochemistry; western blotting; microdissection; morphology; stereology and PCR have been used. Others studies using human prostatic cells (in vitro) focusing on prostatic cancer; hormonal imbalance; and biological processes (angiogenesis; inflammation; and oxidative stress) have also been developed.

Teaching activities

Anatomy: Anatomy for different undergraduate courses (Biological Sciences, Dance, Nursing, Pharmacy and Medicine)

Selected Publications

cagnon, Valéria Helena Alves; Garcia, Progresso José; Guazelli Filho, José; Martinez, F. E.; Mello Jr, W.; Martinez, Marcelo; Ultrastructural study of the lateral lobe of the prostate of wistar rats submitted to experimental chronic alcohol ingestion.. Journal of Submicroscopic Cytology and Pathology, v.30, p. 77-84, 1998

Kido, Larissa Akemi; Montico, Fabio; Sauce, Rafael; Macedo, Aline Barbosa; Minatel, Elaine; Costa, Débora Barbosa Vendramini; De Carvalho, João Ernesto; Pilli, Ronaldo Aloise; cagnon, Valeria Helena Alves; Anti-inflammatory therapies in TRAMP mice: delay in PCa progression. Endocrine Related Cancer, v.23, p. 235-250, 2016 [ doi:10.1530/ERC-15-0540 ]

Da Silva, Raquel Frenedoso; Dhar, Deepanshi; Raina, Komal; Kumar, Dileep; Kant, Rama; cagnon, Valeria Helena Alves; Agarwal, Chapla; Agarwal, Rajesh; Nintedanib inhibits growth of human prostate carcinoma cells by modulating both cell cycle and angiogenesis regulators. Scientific Reports, v.8, p. 9540-, 2018 [ doi:10.1038/s41598-018-27831-1 ]

Lamas, C. A.; Kido, L. A.; Montico, F.; Collares-buzato, C. B.; Maróstica, M. R.; cagnon, V. H. A.; A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. Food & Function, v.11, p. 1547-1559, 2020 [ doi:10.1039/c9fo02621e ]

Lamas, Celina A.; Kido, Larissa A.; Hermes, Túlio A.; Nogueira'lima, Ellen; Minatel, Elaine; Collares'buzato, Carla B.; Maróstica, Mário R.; cagnon, Valéria h. A.; Brazilian berry extract ( Myrciaria jaboticaba ): A promising therapy to minimize prostatic inflammation and oxidative stress. The Prostate, v.1, p. 1-13, 2020 [ doi:10.1002/pros.24017 ]