Wagner José Fávaro

Personal photo

Cargo: Professor Doutor I

PhD, University of Campinas

Dep. BIOLOGIA ESTRUTURAL E FUNCIONAL, IB, Unicamp, Campinas, SP

favarowj@unicamp.br

Area

  • Biomedical
  • Biotechnology
  • Biology Teaching

Research lines

  • Cell differentiation
  • Extracellular matrix

Academic Background

Professor of Human Anatomy at the State University of Campinas (UNICAMP) and specialist in Uropathology, Urogenital Carcinogenesis, Nanomedicine and Drug Development. He holds a Masters, Doctorate and Post-Doctorate degrees from UNICAMP. He is an international member of the American Society of Clinical Oncology (ASCO) and the European Society for Medical Oncology (ESMO). He has published several scientific articles in national and international journals with a selective editorial policy, as well as book chapters. It has patents filed in Brazil and abroad and registered trademarks, with emphasis on the development process of the OncoTherad immunotherapy. He is on the Top 10,000 list of Latin America's Most Influential Researchers by the Alper-Doger (AD) Scientific Index 2021. He has received numerous awards for his scientific contribution, including the UNICAMP 2020 Inventors Award in the Licensed Technology and Spin-Off Creation categories; "Newton Prado" Medal (2018) for relevant services rendered to the community; Prof. Nelson Rodrigues Netto Jr. of Urology (2018) and; INOVA UNICAMP Award for Initiation to Innovation (2018); in addition to several awards at scientific events. After 15 years of research into urogenital carcinogenesis and nanotechnology, he developed the first 100% Brazilian immunotherapy within a public university. Immunotherapy named OncoTherad (MRB-CFI-1) has been shown to have great potential in reducing different solid tumors. As a result of pre-clinical and clinical studies, in animals and humans, of OncoTherad immunotherapy (MRB-CFI-1), Dr. Wagner José Fávaro created the Center for Immunotherapy and Inflammatory Diseases (CIDI)/UNICAMP, acting as coordinator general. He coordinated the International Cooperation in Research and Development Project by the Ministry of Science, Technology, Innovation and Communications (MCTIC) with Slovenia (2014). He was the main representative of the Ministry of Science and Technology (MCTI) at the Consortium Brazil European Community, called NANoREG (The common European approach to regulatory testing of Manufactured Nanomaterials) for the establishment of assessment protocols for nanomaterials.

Research activities

His present research interests are uropathology, carcinogenesis, urogenital tumors, immunotherapy, regenerative medicine and nanobiotechnology in oncology. Responsible for the development of the OncoTherad immunomodulator, which has therapeutic application in several tumors.

Teaching activities

Professor of Human Anatomy for different courses in the health and biological sciences. Creator of the Youtube channel: Anatomia Unicamp. This channel has content with a unique and exclusively didactic-scientific objective, destined to the study of Human Anatomy. https://www.youtube.com/c/AnatomiaUnicamp/featured

Selected Publications

Fávaro, Wagner J; Nunes, Odilon S; Seiva, Fabio Rf; Nunes, Iseu S; Woolhiser, Lisa K; Durán, Nelson; Lenaerts, Anne J; Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer. Infectious Agents and Cancer, v.7, p. 14-, 2012 [ doi:10.1186/1750-9378-7-14 ]

Garcia, P. V.; Apolinario, L. M.; Bockelmann, P. K.; Nunes, I.S.; Duran, N; Fávaro, W. J.; Alterations in ubiquitin ligase Siah-2 and its corepressor N-CoR after P-MAPA immunotherapy and anti-androgen therapy: new therapeutic opportunities for non-muscle invasive bladder cancer.. International Journal of Clinical and Experimental Pathology, v.8, p. 4427-4443, 2015

Garcia, Patrick Vianna; Nunes, Odilon Da Silva; Fávaro, Wagner José; Seiva, Fábio Rodrigues Ferreira; Carniato, Amanda Pocol; De Mello Júnior, Wilson; Duran, Nelson; Macedo, Alda Maria; De Oliveira, Alexandre Gabarra; Romih, Rok; Nunes, Iseu Da Silva; Increased toll-like receptors and p53 levels regulate apoptosis and angiogenesis in non-muscle invasive bladder cancer: mechanism of action of P-MAPA biological response modifier. BMC Cancer (Online), v.16, p. 422-, 2016 [ doi:10.1186/s12885-016-2474-z ]

Fávaro, Wagner José; Iantas, Sonia Regina; Gonçalves, Juliana Mattoso; Socca, Eduardo Augusto Rabelo; Duran, Nelson; Billis, Athanase; Alonso, João Carlos Cardoso; Single-arm phase I/II study of the safety and efficacy of OncoTherad immunomodulator in patients BCG-refractory or relapsed non-muscle invasive bladder cancer.. JOURNAL OF CLINICAL ONCOLOGY, v.37, p. e16000-e16000, 2019 [ doi:10.1200/jco.2019.37.15_suppl.e16000 ]

Fávaro, Wagner José; Iantas, Sonia Regina; Gonçalves, Juliana Mattoso; Dias, Queila Cristina; Reis, Ianny Brum; Billis, Athanase; Duran, Nelson; Alonso, João Carlos Cardoso; Role of OncoTherad immunotherapy in the regulation of toll-like receptors-mediated immune system and RANK/RANKL signaling: New therapeutic perspective for non-muscle invasive bladder cancer.. JOURNAL OF CLINICAL ONCOLOGY, v.37, p. e16004-e16004, 2019 [ doi:10.1200/jco.2019.37.15_suppl.e16004 ]