Danilo Ciccone Miguel

Personal photo

Cargo: Professor Doutor I

PhD, University of São Paulo

Dep. BIOLOGIA ANIMAL, IB, Unicamp, Campinas, SP

dcmiguel@unicamp.br

Area

    Research lines

    • Parasites and environmental health
    • Organization and functioning of organisms

    Personal presentation

    BSc - University of Sao Paulo (2005) PhD in Parasitology - University of Sao Paulo (2011). Research Associate - UMD, USA (2011-2013). Assistant Professor at UNICAMP, Campinas-SP, Brazil.

    Research activities

    My main interest in basic research is focused on understanding the mechanisms that allow Leishmania to survive in the intracellular environment. In our Lab, we also study the efficacy of several compounds aiming at the discovery of novel/repurposed drugs for leishmaniasis treatment. https://www.unicamp.br/unicamp/ju/noticias/2021/06/16/qual-e-o-impacto-da-covid-19-nas-doencas-tropicais-negligenciadas

    Teaching activities

    My lectures are focused on "Contemporary Parasitology" and "Biology of Parasite-Host Interactions" for undergraduate and graduate students at UNICAMP.

    Selected Publications

    Alcântara, Laura M.; Ferreira, Thalita C.S.; Gadelha, Fernanda R.; Miguel, Danilo C.; Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis. International Journal for Parasitology-Drugs and Drug Resistance, v.8, p. 430-439, 2018 [ doi:10.1016/j.ijpddr.2018.09.006 ]

    Minori, K.; Rosa, L. B.; Bonsignori, R.; Casini, A.; Miguel, D. C.; Comparing the antileishmanial activity of gold(I) and gold(III) compounds in L. amazonensis and L. braziliensis in vitro. ChemMedChem, v.2020, p. 01-08, 2020 [ doi:10.1002/cmdc.202000536 ]

    Grazzia, N.; B Junior, S.; Garcia, V. L.; Gadelha, F. R.; Miguel, D. C.; Dihydroartemisinin, an active metabolite of artemisinin, interferes with Leishmania braziliensis mitochondrial bioenergetics and survival. PARASITOLOGY RESEARCH, v.120, p. 705-713, 2021 [ doi:10.1007/s00436-020-07019-1 ]

    Miguel, Danilo C.; Brioschi, Mariana B.C.; Rosa, Leticia B.; Minori, Karen; Grazzia, Nathalia; The impact of COVID-19 on neglected parasitic diseases: what to expect?. TRENDS IN PARASITOLOGY, v.37, p. 694-, 2021 [ doi:10.1016/j.pt.2021.05.003 ]